7,17-dioxoandrost-5-en-3-yl acetate
7,17-dioxoandrost-5-en-3-yl acetate
CAS: 1449-61-2
Molecular Formula: C21H28O4
7,17-dioxoandrost-5-en-3-yl acetate - Names and Identifiers
| Name | 7,17-dioxoandrost-5-en-3-yl acetate |
| Synonyms | 7-OXO-DHA 7-KETO-DHEA 7-keto DHEA acetate 3-ACEDYL-7-KETO-DHEA 5-Androsten-3--ol-7,17-dioneacetate 7,17-dioxoandrost-5-en-3-yl acetate Androst-5-en-7,17-dione,3b-acetyloxy Androst-5-en-3-ol-7,17-dione acetate 7-keto Acetate Dehydroepiandrosterone Androst-5-ene-7,17-dione,3beta-acetyloxy 10,13-dimethyl-7,17-dioxo-2,3,4,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-yl acetate |
| CAS | 1449-61-2 |
| EINECS | 683-490-4 |
| InChI | InChI=1/C21H28O4/c1-12(22)25-14-6-8-20(2)13(10-14)11-17(23)19-15-4-5-18(24)21(15,3)9-7-16(19)20/h11,14-16,19H,4-10H2,1-3H3 |
7,17-dioxoandrost-5-en-3-yl acetate - Physico-chemical Properties
| Molecular Formula | C21H28O4 |
| Molar Mass | 344.44 |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Melting Point | 184.5-187.5 °C |
| Boling Point | 479.6±45.0 °C(Predicted) |
| Flash Point | 209.2°C |
| Vapor Presure | 2.32E-09mmHg at 25°C |
| Refractive Index | 1.548 |
7,17-dioxoandrost-5-en-3-yl acetate - Introduction
7,17-dioxoandrost-5-en-3-yl acetate is a chemical with the following properties:
1. Appearance: white to almost white crystalline powder or crystal.
2. Solubility: Soluble in organic solvents, such as ethanol, chloroform and dichloromethane, insoluble in water.
3. Thermal stability: It has certain thermal stability and is not easy to decompose when heated.
This compound is mainly used in the field of medicine, the specific uses are as follows:
1. Progesterone drugs: as an intermediate for the synthesis of progesterone, it can be used to treat female physiological cycle disorders, functional bleeding, amenorrhea, luteal insufficiency and other diseases.
2. Androgen inhibitor: can inhibit the synthesis of androgen, for the treatment of some male hypersexuality, cancer and other diseases.
The preparation of this compound is mainly obtained by chemical synthesis, and the specific steps include:
1. The 7-ketodehydroepiandrosterone Ester was generated by the reaction of 7-ketodehydroepiandrosterone with acetic anhydride under alkaline conditions.
2. By adding acetic acid and alkali catalyst, the esterification reaction is acylated to generate 7,17-dioxoandrost-5-en-3-yl acetate.
Regarding safety information, 7,17-dioxoandrost-5-en-3-yl acetate is a chemical. The following items should be paid attention to when using it:
1. Pay attention to protection: wear protective gloves, goggles and protective clothing and other personal protective equipment during operation to avoid contact with skin and eyes.
2. Storage: should be stored in a dry, ventilated place, away from the fire and oxidant.
3. Pay attention to taboos: prohibit contact with food, beverages and animal feed.
4. Waste disposal: follow local laws and regulations to properly dispose of waste, do not dump.
Please note that the above information is for reference only, and specific operation and use should be carried out in accordance with relevant safety regulations and regulations.
1. Appearance: white to almost white crystalline powder or crystal.
2. Solubility: Soluble in organic solvents, such as ethanol, chloroform and dichloromethane, insoluble in water.
3. Thermal stability: It has certain thermal stability and is not easy to decompose when heated.
This compound is mainly used in the field of medicine, the specific uses are as follows:
1. Progesterone drugs: as an intermediate for the synthesis of progesterone, it can be used to treat female physiological cycle disorders, functional bleeding, amenorrhea, luteal insufficiency and other diseases.
2. Androgen inhibitor: can inhibit the synthesis of androgen, for the treatment of some male hypersexuality, cancer and other diseases.
The preparation of this compound is mainly obtained by chemical synthesis, and the specific steps include:
1. The 7-ketodehydroepiandrosterone Ester was generated by the reaction of 7-ketodehydroepiandrosterone with acetic anhydride under alkaline conditions.
2. By adding acetic acid and alkali catalyst, the esterification reaction is acylated to generate 7,17-dioxoandrost-5-en-3-yl acetate.
Regarding safety information, 7,17-dioxoandrost-5-en-3-yl acetate is a chemical. The following items should be paid attention to when using it:
1. Pay attention to protection: wear protective gloves, goggles and protective clothing and other personal protective equipment during operation to avoid contact with skin and eyes.
2. Storage: should be stored in a dry, ventilated place, away from the fire and oxidant.
3. Pay attention to taboos: prohibit contact with food, beverages and animal feed.
4. Waste disposal: follow local laws and regulations to properly dispose of waste, do not dump.
Please note that the above information is for reference only, and specific operation and use should be carried out in accordance with relevant safety regulations and regulations.
Last Update：2024-04-09 21:21:28
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CAS: 1449-61-2
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Product Name: Androst-5-en-3-ol-7,17-dione acetate Request for quotation
CAS: 1449-61-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 1449-61-2
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
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